The medical field has always been at the forefront of technological innovation. With an ever-growing global population and an increase in diseases like oncological and musculoskeletal disorders, there's an immediate requirement for more advanced medical devices.

Ageing populations and prevalent sedentary lifestyles are only intensifying the need for improved diagnostic and treatment tools. This is where nanotechnology, with its promise of precision and efficiency, is stepping in to redefine the landscape of medical devices.

In a report by Expert Market Research, the global valuation for nanotechnology within the medical devices sector was reported to be USD 7.55 billion. The same report projects a steady ascent in the market, forecasting a CAGR of 10.20% from 2023 through 2028, with an end projection of USD 13.31 billion by 2028.

Highlighting some pivotal trends, the report states, "The increasing healthcare expenditure across the emerging economies, advancements in 3D implants, and the growing efforts of various governments to improve diagnostic and treatment facilities across healthcare units are some of the major trends in the nanotechnology in medical devices market."

This insight underscores the profound influence nanotechnology holds within the medical devices domain.

Broad Applications of the Technology

Nanotechnology, with its ability to manipulate matter on nearly an atomic scale, offers an array of applications in the medical sector.

Active Implantable Devices:

These devices are implanted within the patient's body to perform specific functions or to augment a deficiency. Cardiac rhythm management devices help regulate heartbeats, retinal implants assist those with vision impairments, and modern hearing aids are designed to enhance sound reception for those with hearing challenges.

Biochips:

Biochips are miniature devices that can perform thousands of biological reactions, such as decoding genes, in a few seconds. DNA microarrays, for instance, help in detecting and measuring the expression levels of large numbers of genes simultaneously. Lab-on-chip technologies integrate lab functions on a chip as small as a few millimetres, speeding up the diagnostic processes.

Implantable Materials:

These are specially designed materials used for medical implants. Bone substitutes can be used in place of real bones in surgeries or treatments, ensuring that the body doesn't reject the new material. Dental restorative compounds are used to treat cavities, restore decayed teeth, and help in various other dental procedures, showcasing the transformative potential of implantology.

Medical Textiles and Wound Care:

In the realm of medical care, textiles are not just for comfort. Medical textiles are tailored for therapeutic and healing properties. They play a crucial role in wound care, designed to protect injuries and accelerate the healing process by creating an optimal environment for recovery.

MRI-Guided Minimally Invasive Procedures:

Nanotechnology enhances MRI-guided procedures by introducing tools like guidewires and MRI markers, making interventions safer and more precise. These tools improve measurement accuracy for parameters such as pressures and blood flows while also enhancing device visibility during procedures.

Emerging Entities in the Sector

With advancements in the medical field recognising the significant potential of nanotechnology, numerous startups are stepping forward to harness this advanced technology for their innovations.

Imbed Biosciences, a standout in the realm of nanotech-driven wound care solutions, has secured funding exceeding USD 20 million. Their approach centres on incorporating bioactive molecules into wound dressings and surgical implants, leveraging their proprietary Microlyte Matrix technology platform. These dressings are equipped with antibacterial, anti-biofilm, and pain-relieving features, showcasing the company's dedication to transforming the wound care industry.

Next, with substantial funding of over USD 16 million, is Nanovis, which specialises in spinal implants. Their notable offerings include a porous scaffold with a nano-patterned surface, termed the FortiCore interbody fusion devices. Additionally, they are pioneering an emerging bactericidal technology. Their product line also consists of titanium scaffold implants crafted for intervertebral spaces and an inter-moulded PEEK optima core.

Another company to watch is Nano4Imaging GmbH, a german-based Nanotech company. The firm creates products for minimally invasive procedures that are MRI-visible. Recently, they formed a partnership and signed a letter of intent with international conglomerate Siemens Healthineers. This collaboration aims to allow Nano4Imaging to develop and introduce their TRACKR software, designed to be a guiding system for Siemens Healthineers' MAGNETOM MRI systems to deliver better outcomes for patients. They are currently raising $5 million through a series B round.

Finally, NanoMedical Systems, backed by over USD 7 million in funding, is making significant strides in the medical field. Their prime focus is the creation of state-of-the-art medical devices through their PMDS platform. This platform merges semiconductor technology with biotech and nano-materials. The Personalized Molecular Drug-delivery System (PMDS) is a fusion of semiconductor techniques with biocompatible components, which uses precision nanochannels to modulate drug release, optimising both safety and therapeutic effectiveness. In addition to their work with implants and injectables, they are broadening their scope by developing tools for biomarker enrichment and specialised implants for conditions like cancer.

Conclusion

The integration of nanotechnology into the medical sector signals a significant evolution in healthcare. With robust economic projections and the rise of innovative startups, it's evident that nanotechnology's role in medical devices is not a temporary phenomenon but a foundational shift. The coming decade holds the potential for groundbreaking developments in treatment methods, patient care, and diagnostics. For stakeholders, from investors to healthcare practitioners, the impending advancements in nanotechnology promise a transformative journey ahead in medical sciences.

COMPANIES TO WATCH:

NanoMedical Systems, Nano4Imaging GmbH, Nanovis, Imbed Biosciences.

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Author:

Kate Sivess-Symes

Content Producer and Writer

Nano Magazine | The Breakthrough